Evaluation of Staphylococcal Activity of Garcinia kola Almonds
Ouattara Karamoko
Faculty of Biosciences, Laboratory of Pharmacodynamics-Biochimistry, Felix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d'Ivoire.
Dibi Koffi Saint Didier
Faculty of Biosciences, Laboratory of Pharmacodynamics-Biochimistry, Felix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d'Ivoire.
Kone Monon *
Department of Biochemistry and Genetics, Faculty of Biological Sciences, Peleforo Gon Coulibaly University of Korhogo, BP 1328 Korhogo, Côte d'Ivoire.
Ouattara Abou
Department of Biochemistry and Microbiology, Faculty of Agroforestry, Jean Lorougnon Guédé University of Daloa, BP 150 Daloa, Côte d'Ivoire.
Bagre Issa
Faculty of Biosciences, Laboratory of Pharmacodynamics-Biochimistry, Felix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d'Ivoire.
*Author to whom correspondence should be addressed.
Abstract
The emergence of infectious diseases, particularly staphylococcal infections, treatment failures and the more high cost of treatment of infections caused by resistant staphylococci called to find other care alternatives. This study was initiated to evaluate the antibacterial activity of the aqueous extract from Garcinia kola almonds on the in vitro growth of Staphylococcus aureus strains. The methods of diffusion in agar and liquid media were used for susceptibility testing and MIC and MBC determination. The tests were performed on four strains of S. aureus and one reference strain. The minimum inhibitory concentrations of the extracts ranged from 3.12 mg/mL and 12.5 mg/mL and the minimum bactericidal concentrations between 6.25 mg/mL and 25 mg/mL. The lowest value of MIC and MBC was observed with S. aureus ATCC 29213 while the greatest value of these same parameters was obtained on S. aureus 993C/18 and S. aureus 1075C/18. The aqueous almonds extract of Garcinia kola had a bactericidal activity on all the strains of S. aureus studied. This could justify the use of Garcinia kola almonds in the treatment of various diseases in traditional society.
Keywords: Garcinia kola, aqueous extract, Staphylococcus aureus, MIC, MB