Vitamin D Status of Infertile Women in Abidjan, Côte d'Ivoire
Chantal Yah Kouamé-Dia
*
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire and Abidjan Heart Institute Laboratory, BP V 206 Abidjan, Côte d’Ivoire.
Carine Yao-Yapo
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Kadio Morel Kouacou
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Jean Louis Konan
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire and Abidjan Heart Institute Laboratory, BP V 206 Abidjan, Côte d’Ivoire.
Bénédicte Koné-Dakouri
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Akissi Joelle Koffi
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Minhibo Pohosson
Abidjan Heart Institute Laboratory, BP V 206 Abidjan, Côte d’Ivoire.
Otchoumou Bétina
Abidjan Heart Institute Laboratory, BP V 206 Abidjan, Côte d’Ivoire.
Fatou Koné-Koné
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Eric Sagou Yayo
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Angèle Edjeme-Aké
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
Hugues Ahiboh
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire.
ML Hauhouot-Attoungbré
Biochemistry Laboratory, Faculty of Pharmacy, Félix Houphouët Boigny University of Abidjan, BP V 34, Abidjan, Côte d’Ivoire and Abidjan Heart Institute Laboratory, BP V 206 Abidjan, Côte d’Ivoire.
*Author to whom correspondence should be addressed.
Abstract
Background: Long known for its role in phosphocalcic metabolism, vitamin D has been attracting growing interest in recent years for its involvement in numerous physiological processes, including its essential role in reproductive health.
According to many authors, vitamin D is involved in biological processes crucial to fertility, such as the production of sex hormones (progesterone and estrogen), promoting oocyte maturation and increasing endometrial receptivity for successful implantation. Inadequate vitamin D levels would therefore have a negative impact on fertility. This study determined the vitamin D status of infertile women in Abidjan.
Methods: This was a descriptive cross-sectional study conducted from June 2023 to September 2024. It included 102 infertile women, aged 21-50 years, consulting a specialized clinic in Abidjan and having given their consent to participate in the study. Serum vitamin D [25(OH)D] levels were measured on the Vidas PCÒ, and the prevalence of hypovitaminosis D (levels < 30 ng/ml) was determined.
Results: The mean age of the patients was 37±6 years. The mean vitamin D level in the infertile population was 24.07 ± 7.69 ng/ml.
The prevalence of hypovitaminosis D (level < 30 ng/ml) was 81.37%.
Only 18.63% of women had optimal serum vitamin D levels (30-100 ng/ml).
Conclusion: The prevalence of hypovitaminosis D in infertile women in Abidjan is high (81.37%). These results highlight the need to monitor and correct vitamin D levels in infertile women for better management of fertility disorders.
Keywords: Vitamin D, prevalence, hypovitaminosis D, infertility