Phytochemical Composition, Antibacterial Activities against Multi-Resistant Strains of Pseudomonas aeruginosa and Acinetobacter baumannii of the Bark Extract of Ficus platyphylla Dell. Holl.

Jean Brice Bredou

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.

Demel Axel Adou *

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire and Département des Sciences et Techniques, Université Alassane Ouattara, 01 BP 18 Bouaké 01, Côte d’Ivoire.

Zlankeuhon Jérôme Sahi

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.

Koffi Appolinaire Yeboué

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.

Guy Roger Mida Kabran

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.

Benson Boua Boua

Laboratoire de Chimie Bio-Organique et de Substances Naturelles, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire.

*Author to whom correspondence should be addressed.


Ficus platyphylla Ficus platyphylla belongs to the Moraceae family which contains nearly 1400 species divided into around forty genera. It is used to manage several diseases in folklore medicine. This study focused on the phytochemical screening and evaluation of the antibacterial potential against Pseudomona aeruginosa and Acinetobacter baumannii of hydroethanolic extract from Ficus platyphylla (FP) bark. Phytochemical and antibacterial activity were carried out according to the literature procedure. Qualitative analyses of FP revealed the presence polyphenols, flavonoids, coumarins, tannins, alkaloids, sterols and terpenes. Quantitative analysis by spectrophotometry showed a phenolic compound content to be 0.878 ± 0.02 mg EAG/g DM. The flavonoids content was 0.084 ± 0.02 mg EQ/g DM, while flavonic aglycones, anthocyanins and condensed tannins were 0.014 mg EQ/g DM, 0.018 mg EQ/g DM and 0.189 mg EC/g DM, respectively. In vivo antibacterial activity showed that (FP) was ineffective against six (06) multi-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii.

Keywords: Ficus platyphylla, phytochemical screening, P. aeruginosa, A. baumannii

How to Cite

Bredou, Jean Brice, Demel Axel Adou, Zlankeuhon Jérôme Sahi, Koffi Appolinaire Yeboué, Guy Roger Mida Kabran, and Benson Boua Boua. 2024. “ Holl”. International Journal of Biochemistry Research & Review 33 (6):17-25.


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