A Comparative Study of the Anti-Candidal Activity of Four Medicinal Plants Used in Côte d'Ivoire
Yapo Y. C. V.
UFR des Sciences et Techniques, Université Alassane Ouattara, BPV 18 Bouaké 01, Côte d’Ivoire.
Kra A. K. M.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Konan G. K. N. A. *
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Kple T. K. M.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Money Y. U.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Kouame C. C.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Bolou G. E. K.
Centre National Floristique, 22 BP 582 Abidjan 22, Côte d’Ivoire
N’guessan J. D.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire.
Djaman A. J.
Laboratoire Biologie et Santé, Université Félix Houphouet-Boigny, 22 BP 582 Abidjan 01, Côte d’Ivoire and Institut Pasteur of Côte d’Ivoire, 01 BP 490 Abidjan 01, Côte d’Ivoire.
*Author to whom correspondence should be addressed.
Abstract
Some plants groups are used by traditional practitioners to treat infectious diseases. The ongoing development of antibiotic resistance continues to have a lasting impact on public health. This study aimed to assess the potential activity of the medicinal plants found in Ivorian soil. Spectrometric measurements was employed in addition to the moss test, revealed the presence of sterols and polyterpenes, polyphenolic compounds, saponins, quinones, alkaloids, and tannins in the extracts of the four plants studied. The use of the double dilution method in tilted tubes revealed the Anti-candida potential of the plant extracts. Results revealed showed that the hydroethanolic extract of T. mantaly produced the lowest MFC (3.125 mg/mL) and IC50 (0.3 mg/mL) values. It was followed by Z. gilletii (MFC = 3.125 mg/mL; IC50 = 0.62 mg/mL) and T. catappa (MFC = 3.125 mg/mL; IC50 = 0.68 mg/mL). No significant inhibition was observed with the extracts of A. occidentale. This study contributes to the valorization of medicinal plants and the floral heritage of Côte d'Ivoire.
Keywords: Anticandidosis activity, extraction, medicinal plants