Effect of the Aqueous Extract of Corchorus olitorius L. on the Lipid Parameters of Rats Subjected to a Hyperlipidic Diet
Kamenan Koua Christ Delor *
Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire.
Brahima Kouamé Koffi Raoul
Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire.
Ackah Jacques Auguste Alfred Bognan
Department of Biochemistry-Microbiology, UFR Agroforestry, Jean Lorougnon Guédé University, Côte d’Ivoire.
*Author to whom correspondence should be addressed.
Abstract
Background: Advances in physiological data, clinical research and medico-economic findings have led to considering obesity as a pathogenic situation, even a real disease. Measures should be taken to stop the spread of this pathology associated with abnormalities in glucose and lipid metabolism. Thus, a plant species was tested to assess its effect on lipid parameters.
Method: the aqueous extract of the plant Corchorus olitorius L. was tested on female rats subjected to a hyperlipidic diet and the biochemical parameters were evaluated. In addition, a phytochemical characterization was carried out.
Results: The high fat diet led to overeating and weight gain. The aqueous extract of Corchorus olitorius L. contains bioactive molecules, which favored the reduction of plasma and tissue levels of cholesterol, triglycerides, LDL and an increase in HDL levels in rats subjected to a hyperlipidic diet.
Conclusion: The aqueous extract of Corchorus olitorius L. has beneficial effects on lipid disorders.
Keywords: High fat diet, lipid parameters, Corchorus olitorius L.