Immune Modulatory Properties of Powdered Telfairia occidentalis Supplemented Vital Feed Diet on Male Wistar Rats
Kunle Ogungbemi *
Department of Chemistry/Biochemistry, Nigerian Stored Products Research Institute, Ibadan Zonal Office, Ibadan, Oyo State, Nigeria.
C. A. Moses
Department of Biochemistry, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria.
D. T. Ishola
Department of Chemistry/Biochemistry, Nigerian Stored Products Research Institute, Ibadan Zonal Office, Ibadan, Oyo State, Nigeria.
T. A. Odeniyi
Department of Chemistry/Biochemistry, Nigerian Stored Products Research Institute, Ibadan Zonal Office, Ibadan, Oyo State, Nigeria.
A. O. Oyeniran
Department of Biochemistry, Alhikmah University, Ilorin, Kwara State, Nigeria.
A. O. Alejo
Department of Entomology, Nigerian Stored Products Research Institute, Headquarters, Ilorin, Kwara State, Nigeria.
O. T. Ishola
Department of Microbiology, Federal University of Technology, Akure, Ondo State, Nigeria.
S. I. Ayanda
Department of Chemistry/Biochemistry, Nigerian Stored Products Research Institute, Headquarters, Ilorin, Kwara State, Nigeria.
A. A. Afolabi
Department of Entomology, Nigerian Stored Products Research Institute, Headquarters, Ilorin, Kwara State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
This study was carried out to investigate the immune modulatory properties of different graded stored powdered of Telfairia occidentalis supplemented diet on male wistar rats. Twelve male wistar rats weighing 120g±20g were purchased, acclimatised and randomly allotted into four (T1, T2, T3, T4) Telfairia occidentalis supplemented groups (0% 5%, 10% and 15%). The rate of their feeding was monitored for three weeks after which the animals were decapitated and the blood and organs were removed for haematological and endogenous antioxidant analysis. The result showed that the highest feed intake was observed in animal fed with the highest level of Telfairia occidentalis supplementation. Also from the haematological analysis, the white blood cell of the highest supplementation was boosted when compared to other graded level likewise the endogenous Antioxidant level was enhanced when compared with the control group.
Keywords: Endogenous antioxidants, exogenous antioxidant, haematological parameters, immune modulatory properties, Telfairia occidentalis