Studies on Anti Typhoid Properties of Aqueous Methanol Leaves Extract of Albizia ferruginea (Musase)
S. Sarkiyayi *
Biochemistry/Chemistry Section, Department of Applied Science, Kaduna Polytechnic, Kaduna, Nigeria
J. Karago
Biology/Microbiology Section, Department of Applied Science, Kaduna Polytechnic, Kaduna, Nigeria
R. Hassan
44 Reference Hospital, Kaduna, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Anti typhoid properties of aqueous methanol leaves extract of Albizia ferruginea (musase) was investigated in the present study. The phytochemical screening of the aqueous methanol leave extract of Albizia ferruginea revealed the presence of alkaloid, anthraquinines, carbohydrates, cardiac glycosides, flavonoid, saponin, tannin and terpens. The leave extract of Albizia ferruginea does not possess acute toxicity effect on animal (mice) with a dose of (LD50) 5000mg/kg. The plant extract produced inhibitory activities against Salmonella typhi with a minimum inhibitory concentration of 1000μg/ml. The plant extract is effective as anti typhoid agent against Salmonella typhi on mice infected with typhoid parasites as shown by widal test.
Keywords: Albizia ferruginea, Salmonella typhi, plant, Anti typhoid